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Codeine Brand names, Codeine Analogs

Codeine Brand Names Mixture

  • No information avaliable

Codeine Chemical_Formula

C18H21NO3

Codeine RX_link

http://www.rxlist.com/cgi/generic/codphos.htm

Codeine fda sheet

Codeine msds (material safety sheet)

Codeine MSDS

Codeine Synthesis Reference

Goto, Yamamoto, Proc. Japan Acad. 30, 769 (1954)

Codeine Molecular Weight

299.364 g/mol

Codeine Melting Point

154 - 156 oC

Codeine H2O Solubility

<0.1 g/100 mL

Codeine State

solid

Codeine LogP

1.809

Codeine Dosage Forms

Oral solution; Tablet

Codeine Indication

For treatment and management of pain (Systemic), also used as an Antidiarrheal and as a cough suppressant.

Codeine Pharmacology

Codeine, an opiate agonist in the CNS, is similar to other phenanthrene derivatives such as morphine. Codeine, in combination with guaifenesin or iodinated glycerol, is used as a cough suppressant and, as a single agent or in combination with acetaminophen or other products, is used for pain control and as an antidiarrheal agent.

Codeine Absorption

well absorbed

Codeine side effects and Toxicity

Respiratory depression, sedation and miosis and common symptoms of overdose. Other symptoms include nausea, vomiting, skeletal muscle flaccidity, bradycardia, hypotension, and cool, clammy skin. Apnea and death may ensue

Codeine Patient Information

Codeine may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, s.c. as driving a car or operating machinery. Codeine in combination with other narcotic analgesics, phenothiazines, sedative hypnotics, and alcohol has additive depressant effects.

Codeine Organisms Affected

Humans and other mammals