Closina
Closina Brand names, Closina Analogs
- Cicloserina
- Closerin
- Closina
- Cyclomycin
- Cyclorin
- Cycloserin
- Cycloserine, D-
- D-CS
- D-Cycloserine
- D-Cycloserine synth. BP 88
- D-Cycloserine, synthetic
- D-Oxamicina
- D-Oxamycin
- DL-Cycloserine
- Farmiserina
- Farmiserine
- L-Cycloserine
- Micoserina
- Miroserina
- Miroseryn
- Novoserin
- Orientomycin
- Oxamicina
- Oxamycin
- Oxymycin
- Seromycin
- Tebemicina
- Tisomycin
- Wasserina
- alpha-Cycloserine
Closina Brand Names Mixture
- No information avaliable
Closina Chemical_Formula
C3H6N2O2
Closina RX_link
No information avaliable
Closina fda sheet
Closina msds (material safety sheet)
Closina Synthesis Reference
No information avaliable
Closina Molecular Weight
102.092 g/mol
Closina Melting Point
147 oC
Closina H2O Solubility
Soluble
Closina State
Solid
Closina LogP
-1.631
Closina Dosage Forms
Capsules (red and gray capsules, oral, 250mg)
Closina Indication
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Closina Pharmacology
Cycloserine, a broad-spectrum antibiotic, may be bactericidal or bacteriostatic, depending on its concentration at the site of infection and the susceptibility of the organism. Cycloserine works by blocking the formation of these peptidoglycans. By doing this the walls of the bacteria become weak and it results in the death of the bacteria
Closina Absorption
Rapidly and almost completely absorbed (70 to 90%) from the gastrointestinal tract following oral administration.
Closina side effects and Toxicity
Oral LD50 in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
Closina Patient Information
Closina Organisms Affected
Enteric bacteria and other eubacteria
