Clobetasol en es it fr

Clobetasol Brand names, Clobetasol Analogs

Clobetasol Brand Names Mixture

  • No information avaliable

Clobetasol Chemical_Formula

C25H32ClFO5

Clobetasol RX_link

http://www.rxlist.com/cgi/generic/olux.htm

Clobetasol fda sheet

Clobetasol FDA

Clobetasol msds (material safety sheet)

Clobetasol MSDS

Clobetasol Synthesis Reference

No information avaliable

Clobetasol Molecular Weight

466.97 g/mol

Clobetasol Melting Point

195.5-197 oC

Clobetasol H2O Solubility

3.86 mg/L

Clobetasol State

Solid

Clobetasol LogP

3.588

Clobetasol Dosage Forms

Foam (0.05%) and ointment (usp 0.05%, supplied in 15 g, 30 g, and 45 g tubes)

Clobetasol Indication

For short-term topical treatment of the inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp.

Clobetasol Pharmacology

Like other topical corticosteroids, clobetasol has anti-inflammatory, antipruritic, and vasoconstrictive properties. It is a very high potency topical corticosteroid that should not be used with occlusive dressings. It is recommended that treatment should be limited to 2 consecutive weeks and therapy should be discontinued when adequate results have been achieved.

Clobetasol Absorption

Topical corticosteroids can be absorbed from intact healthy skin. The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle and the integrity of the epidermal barrier. Occlusion, inflammation and/or other disease processes in the skin may also increase percutaneous absorption.

Clobetasol side effects and Toxicity

Oral LD50 in rat and mouse is >3000 mg/kg. Topically applied clobetasol can be absorbed in sufficient amounts to produce systemic effects. Symptoms of overdose include thinning of skin and suppression of adrenal cortex (decreased ability to respond to stress).

Clobetasol Patient Information

Clobetasol Organisms Affected

Humans and other mammals