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Cimetidine Brand names, Cimetidine Analogs

Cimetidine Brand Names Mixture

  • No information avaliable

Cimetidine Chemical_Formula

C10H16N6S

Cimetidine RX_link

http://www.rxlist.com/cgi/generic/cimet.htm

Cimetidine fda sheet

Cimetidine FDA

Cimetidine msds (material safety sheet)

Cimetidine Synthesis Reference

G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)

Cimetidine Molecular Weight

252.34 g/mol

Cimetidine Melting Point

142 oC

Cimetidine H2O Solubility

0.5 g/100 mL

Cimetidine State

Solid

Cimetidine LogP

0.879

Cimetidine Dosage Forms

Tablets; Oral solution

Cimetidine Indication

For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion

Cimetidine Pharmacology

Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Cimetidine Absorption

Rapid 60-70%

Cimetidine side effects and Toxicity

nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.

Cimetidine Patient Information

Cimetidine Organisms Affected

Humans and other mammals