Cholestat Brand names, Cholestat Analogs
Cholestat Brand Names Mixture
Cholestat fda sheet
Cholestat msds (material safety sheet)
Cholestat Synthesis Reference
W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)
Cholestat Molecular Weight
Cholestat Melting Point
Cholestat H2O Solubility
Cholestat Dosage Forms
For the treatment of hypercholesterolemia.
Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.
Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.
Cholestat side effects and Toxicity
No information avaliable
Cholestat Patient Information
Patients should be advised about substances they should not take concomitantly with simvastatin and be
advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to
inform other physicians prescribing a new medication that they are taking ZOCOR.
Cholestat Organisms Affected
Humans and other mammals