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Chloraminophene Brand names, Chloraminophene Analogs

Chloraminophene Brand Names Mixture

  • No information avaliable

Chloraminophene Chemical_Formula

C14H19Cl2NO2

Chloraminophene RX_link

http://www.rxlist.com/cgi/generic2/leukeran.htm

Chloraminophene fda sheet

Chloraminophene FDA

Chloraminophene msds (material safety sheet)

Chloraminophene MSDS

Chloraminophene Synthesis Reference

No information avaliable

Chloraminophene Molecular Weight

304.212 g/mol

Chloraminophene Melting Point

65 oC

Chloraminophene H2O Solubility

1.24E+004 mg/L

Chloraminophene State

Solid

Chloraminophene LogP

3.25

Chloraminophene Dosage Forms

Tablet

Chloraminophene Indication

For treatment of chronic lymphatic (lymphocytic) leukemia, malignant lymphomas including lymphosarcoma, giant follicular lymphoma, and Hodgkin's disease

Chloraminophene Pharmacology

Chlorambucil is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.

Chloraminophene Absorption

No information avaliable

Chloraminophene side effects and Toxicity

No information avaliable

Chloraminophene Patient Information

No information avaliable

Chloraminophene Organisms Affected

Humans and other mammals