Cetylpyridinium chloride monohydrate
Category
Cetylpyridinium chloride monohydrate Brand names, Cetylpyridinium chloride monohydrate Analogs
Cetylpyridinium chloride monohydrate Brand Names Mixture
Cetylpyridinium chloride monohydrate Chemical_Formula
No information avaliable
Cetylpyridinium chloride monohydrate RX_link
http://www.rxlist.com/cgi/generic2/cetrorelix.htm
Cetylpyridinium chloride monohydrate fda sheet
Cetylpyridinium chloride monohydrate msds (material safety sheet)
Cetylpyridinium chloride monohydrate Synthesis Reference
No information avaliable
Cetylpyridinium chloride monohydrate Molecular Weight
1431.06 g/mol
Cetylpyridinium chloride monohydrate Melting Point
No information avaliable
Cetylpyridinium chloride monohydrate H2O Solubility
No information avaliable
Cetylpyridinium chloride monohydrate State
Solid
Cetylpyridinium chloride monohydrate LogP
No information avaliable
Cetylpyridinium chloride monohydrate Dosage Forms
Powder for solution
Cetylpyridinium chloride monohydrate Indication
For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation.
Cetylpyridinium chloride monohydrate Pharmacology
Cetrorelix is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Due to a positive estradiol (E2) feedback at midcycle, GnRH liberation is enhanced resulting in an LH-surge. This LH-surge induces the ovulation of the dominant follicle, resumption of oocyte meiosis and subsequently luteinization as indicated by rising progesterone levels. Cetrorelix competes with natural GnRH for binding to membrane receptors on pituitary cells and thus controls the release of LH and FSH in a dose-dependent manner.
Cetylpyridinium chloride monohydrate Absorption
Rapidly absorbed following subcutaneous injection. The mean absolute bioavailability following subcutaneous administration to healthy female subjects is 85%.
Cetylpyridinium chloride monohydrate side effects and Toxicity
No information avaliable
Cetylpyridinium chloride monohydrate Patient Information
Cetylpyridinium chloride monohydrate Organisms Affected
Humans and other mammals
