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Cetrotide Brand names, Cetrotide Analogs

Cetrotide Brand Names Mixture

  • No information avaliable

Cetrotide Chemical_Formula

No information avaliable

Cetrotide RX_link

http://www.rxlist.com/cgi/generic2/cetrorelix.htm

Cetrotide fda sheet

Cetrotide FDA

Cetrotide msds (material safety sheet)

Cetrotide Synthesis Reference

No information avaliable

Cetrotide Molecular Weight

1431.06 g/mol

Cetrotide Melting Point

No information avaliable

Cetrotide H2O Solubility

No information avaliable

Cetrotide State

Solid

Cetrotide LogP

No information avaliable

Cetrotide Dosage Forms

Powder for solution

Cetrotide Indication

For the inhibition of premature LH surges in women undergoing controlled ovarian stimulation.

Cetrotide Pharmacology

Cetrorelix is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Due to a positive estradiol (E2) feedback at midcycle, GnRH liberation is enhanced resulting in an LH-surge. This LH-surge induces the ovulation of the dominant follicle, resumption of oocyte meiosis and subsequently luteinization as indicated by rising progesterone levels. Cetrorelix competes with natural GnRH for binding to membrane receptors on pituitary cells and thus controls the release of LH and FSH in a dose-dependent manner.

Cetrotide Absorption

Rapidly absorbed following subcutaneous injection. The mean absolute bioavailability following subcutaneous administration to healthy female subjects is 85%.

Cetrotide side effects and Toxicity

No information avaliable

Cetrotide Patient Information

Cetrotide Organisms Affected

Humans and other mammals