Cerivastatin sodium
Cerivastatin sodium Brand names, Cerivastatin sodium Analogs
Cerivastatin sodium Brand Names Mixture
- No information avaliable
Cerivastatin sodium Chemical_Formula
C26H34FNO5
Cerivastatin sodium RX_link
http://www.rxlist.com/cgi/generic2/cerivastat.htm
Cerivastatin sodium fda sheet
Cerivastatin sodium msds (material safety sheet)
Cerivastatin sodium Synthesis Reference
Angerbauer R, Bischoff H, Steinke W and Ritter W (1994) BAY w 6228. Drugs Fut 19: 537-541.
Cerivastatin sodium Molecular Weight
459.55 g/mol
Cerivastatin sodium Melting Point
No information avaliable
Cerivastatin sodium H2O Solubility
Highly solubility
Cerivastatin sodium State
Solid
Cerivastatin sodium LogP
4.669
Cerivastatin sodium Dosage Forms
Tablet
Cerivastatin sodium Indication
Used as an adjunct to diet for the reduction of elevated total and LDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia (Fredrickson Types IIa and IIb) when the response to dietary restriction of saturated fat and cholesterol and other non-pharmacological measures alone has been inadequate.
Cerivastatin sodium Pharmacology
Cerivastatin, a competitive HMG-CoA reductase inhibitor effective in lowering LDL cholesterol and triglycerides, is used to treat primary hypercholesterolemia and mixed dyslipidemia (Fredrickson types IIa and IIb).
Cerivastatin sodium Absorption
The mean absolute oral bioavailability 60% (range 39 - 101%).
Cerivastatin sodium side effects and Toxicity
Rhabdomyolysis, liver concerns
Cerivastatin sodium Patient Information
Patients should be advised to report promptly unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever.
Cerivastatin sodium Organisms Affected
Humans and other mammals
