Cerezyme (Genzyme Corp)
Cerezyme (Genzyme Corp) Brand names, Cerezyme (Genzyme Corp) Analogs
Cerezyme (Genzyme Corp) Brand Names Mixture
- No information avaliable
Cerezyme (Genzyme Corp) Chemical_Formula
C2532H3854N672O711S16
Cerezyme (Genzyme Corp) RX_link
http://www.rxlist.com/cgi/generic2/imiglucerase.htm
Cerezyme (Genzyme Corp) fda sheet
Cerezyme (Genzyme Corp) msds (material safety sheet)
Cerezyme (Genzyme Corp) Synthesis Reference
No information avaliable
Cerezyme (Genzyme Corp) Molecular Weight
55597.4
Cerezyme (Genzyme Corp) Melting Point
No information avaliable
Cerezyme (Genzyme Corp) H2O Solubility
No information avaliable
Cerezyme (Genzyme Corp) State
Liquid
Cerezyme (Genzyme Corp) LogP
-0.168
Cerezyme (Genzyme Corp) Dosage Forms
Powder for solution; Solution (IV injection)
Cerezyme (Genzyme Corp) Indication
For the treatment of Gaucher's disease (deficiency in glucocerebrosidase)
Cerezyme (Genzyme Corp) Pharmacology
Gaucher disease is characterized by a functional deficiency in Beta-glucocerebrosidase enzymatic activity and the resultant accumulation of lipid glucocerebroside in tissue macrophages which become engorged and are termed Gaucher cells. Gaucher cells are typically found in liver, spleen and bone marrow. This can lead to an enlarged spleen and liver (hepatosplenomegaly). Secondary hematologic sequelae include severe anemia and thrombocytopenia. Injections of imiglucerase into Gaucher disease patients leads to elevated serum levels of the enzyme and reduction in the accumulation of glucocerebroside leading to reduced anemia and thrombocytopenia, reduced spleen and liver size, and decreased cachexia
Cerezyme (Genzyme Corp) Absorption
No information avaliable
Cerezyme (Genzyme Corp) side effects and Toxicity
No information avaliable
Cerezyme (Genzyme Corp) Patient Information
No information avaliable
Cerezyme (Genzyme Corp) Organisms Affected
Humans and other mammals
