Cefmetazole
Cefmetazole Brand names, Cefmetazole Analogs
Cefmetazole Brand Names Mixture
- No information avaliable
Cefmetazole Chemical_Formula
C15H17N7O5S3
Cefmetazole RX_link
No information avaliable
Cefmetazole fda sheet
Cefmetazole msds (material safety sheet)
Cefmetazole Synthesis Reference
No information avaliable
Cefmetazole Molecular Weight
471.538 g/mol
Cefmetazole Melting Point
No information avaliable
Cefmetazole H2O Solubility
94.2 mg/L
Cefmetazole State
No information avaliable
Cefmetazole LogP
-1.063
Cefmetazole Dosage Forms
Solution for injection
Cefmetazole Indication
For the treatment of infections caused by susceptible organisms.
Cefmetazole Pharmacology
Cefmetazole is a second-generation cephalosporin. The cephalosporins are bactericidal drugs with both gram-positive and gram-negative activity. They inhibit bacterial cell wall synthesis in a way similar to the penicillins. Cefmetazole is more active than 1st-generation cephalosporins against indole-positive Proteus, Serratia, anaerobic gram-negative bacilli (including B. fragilis), and some E. coli, Klebsiella, and P. mirabilis, but is less active than cefoxitin or cefotetan against most gram-negative bacilli.
Cefmetazole Absorption
Bioavailability is approximately 100% following intramuscular injection.
Cefmetazole side effects and Toxicity
Oral LD50 in rats is 3,204 mg/kg. With other b-lactam antibiotics, adverse effects following overdosage have included nausea, vomiting, epigastric distress, diarrhea, and convulsions.
Cefmetazole Patient Information
No information avaliable
Cefmetazole Organisms Affected
Enteric bacteria and other eubacteria
