Cefixoral

Cefixoral Brand names, Cefixoral Analogs

Cefixoral Brand Names Mixture

No information avaliable

Cefixoral Chemical_Formula

C₁₆H₁₅N₅O₇S₂

Cefixoral RX_link

http://www.rxlist.com/cgi/generic/cefixime.htm

Cefixoral fda sheet

Cefixoral FDA

Cefixoral msds (material safety sheet)

Cefixoral MSDS

Cefixoral Synthesis Reference

T. Takaya et al., U.S. Pat. 4,409,214 (1981)

Cefixoral Molecular Weight

453.452 g/mol

Cefixoral Melting Point

218-225 ^oC

Cefixoral H₂O Solubility

55.11 mg/L

Cefixoral State

Solid

Cefixoral LogP

-0.559

Cefixoral Dosage Forms

Oral suspension (100 mg/5 mL); Tablet (200 mg and 400 mg); Powder for solution; Powder for suspension

Cefixoral Indication

For use in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: (1) uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis, (2) otitis media caused by Haemophilus influenzae (beta-lactamase positive and negative strains), Moraxella catarrhalis (most of which are beta-lactamase positive), and S. pyogenes, (3) pharyngitis and tonsillitis caused by S. pyogenes, (4) acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae (beta-lactamase positive and negative strains), and (5) uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae (penicillinase- and non-penicillinase-producing strains).

Cefixoral Pharmacology

Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall.

Cefixoral Absorption

About 40%-50% absorbed orally whether administered with or without food, however, time to maximal absorption is increased approximately 0.8 hours when administered with food.

Cefixoral side effects and Toxicity

Symptoms of overdose include blood in the urine, diarrhea, nausea, upper abdominal pain, and vomiting.

Cefixoral Patient Information

Cefixoral Organisms Affected

Enteric bacteria and other eubacteria