PharmacyCodes



Cefiximum [Latin] en es it fr

Cefiximum [Latin] Brand names, Cefiximum [Latin] Analogs

Cefiximum [Latin] Brand Names Mixture

  • No information avaliable

Cefiximum [Latin] Chemical_Formula

C16H15N5O7S2

Cefiximum [Latin] RX_link

http://www.rxlist.com/cgi/generic/cefixime.htm

Cefiximum [Latin] fda sheet

Cefiximum_[Latin] FDA

Cefiximum [Latin] msds (material safety sheet)

Cefiximum_[Latin] MSDS

Cefiximum [Latin] Synthesis Reference

T. Takaya et al., U.S. Pat. 4,409,214 (1981)

Cefiximum [Latin] Molecular Weight

453.452 g/mol

Cefiximum [Latin] Melting Point

218-225 oC

Cefiximum [Latin] H2O Solubility

55.11 mg/L

Cefiximum [Latin] State

Solid

Cefiximum [Latin] LogP

-0.559

Cefiximum [Latin] Dosage Forms

Oral suspension (100 mg/5 mL); Tablet (200 mg and 400 mg); Powder for solution; Powder for suspension

Cefiximum [Latin] Indication

For use in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: (1) uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis, (2) otitis media caused by Haemophilus influenzae (beta-lactamase positive and negative strains), Moraxella catarrhalis (most of which are beta-lactamase positive), and S. pyogenes, (3) pharyngitis and tonsillitis caused by S. pyogenes, (4) acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae (beta-lactamase positive and negative strains), and (5) uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae (penicillinase- and non-penicillinase-producing strains).

Cefiximum [Latin] Pharmacology

Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall.

Cefiximum [Latin] Absorption

About 40%-50% absorbed orally whether administered with or without food, however, time to maximal absorption is increased approximately 0.8 hours when administered with food.

Cefiximum [Latin] side effects and Toxicity

Symptoms of overdose include blood in the urine, diarrhea, nausea, upper abdominal pain, and vomiting.

Cefiximum [Latin] Patient Information

Cefiximum [Latin] Organisms Affected

Enteric bacteria and other eubacteria