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Cefixime_Anhydrous
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Cefixime Anhydrous Brand names, Cefixime Anhydrous Analogs

Cefixime Anhydrous Brand Names Mixture

  • No information avaliable

Cefixime Anhydrous Chemical_Formula

C16H15N5O7S2

Cefixime Anhydrous RX_link

http://www.rxlist.com/cgi/generic/cefixime.htm

Cefixime Anhydrous fda sheet

Cefixime_Anhydrous FDA

Cefixime Anhydrous msds (material safety sheet)

Cefixime_Anhydrous MSDS

Cefixime Anhydrous Synthesis Reference

T. Takaya et al., U.S. Pat. 4,409,214 (1981)

Cefixime Anhydrous Molecular Weight

453.452 g/mol

Cefixime Anhydrous Melting Point

218-225 oC

Cefixime Anhydrous H2O Solubility

55.11 mg/L

Cefixime Anhydrous State

Solid

Cefixime Anhydrous LogP

-0.559

Cefixime Anhydrous Dosage Forms

Oral suspension (100 mg/5 mL); Tablet (200 mg and 400 mg); Powder for solution; Powder for suspension

Cefixime Anhydrous Indication

For use in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: (1) uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis, (2) otitis media caused by Haemophilus influenzae (beta-lactamase positive and negative strains), Moraxella catarrhalis (most of which are beta-lactamase positive), and S. pyogenes, (3) pharyngitis and tonsillitis caused by S. pyogenes, (4) acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae (beta-lactamase positive and negative strains), and (5) uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae (penicillinase- and non-penicillinase-producing strains).

Cefixime Anhydrous Pharmacology

Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall.

Cefixime Anhydrous Absorption

About 40%-50% absorbed orally whether administered with or without food, however, time to maximal absorption is increased approximately 0.8 hours when administered with food.

Cefixime Anhydrous side effects and Toxicity

Symptoms of overdose include blood in the urine, diarrhea, nausea, upper abdominal pain, and vomiting.

Cefixime Anhydrous Patient Information

Cefixime Anhydrous Organisms Affected

Enteric bacteria and other eubacteria