Cefa -ak
Cefa -ak Brand names, Cefa -ak Analogs
Cefa -ak Brand Names Mixture
- Isotamine B 300 (Isoniazid + Pyridoxine Hydrochloride)
- Rifater (Isoniazid + Pyrazinamide + Rifampin)
Cefa -ak Chemical_Formula
C17H17N3O6S2
Cefa -ak RX_link
No information avaliable
Cefa -ak fda sheet
Cefa -ak msds (material safety sheet)
Cefa -ak Synthesis Reference
No information avaliable
Cefa -ak Molecular Weight
423.466 g/mol
Cefa -ak Melting Point
No information avaliable
Cefa -ak H2O Solubility
1030 mg/L
Cefa -ak State
Solid
Cefa -ak LogP
-0.251
Cefa -ak Dosage Forms
Gel; Suspension
Cefa -ak Indication
For treatment of infections caused by susceptible bacteria.
Cefa -ak Pharmacology
Cephapirin is a first-generation cephalosporin that has a wide spectrum of activity against gram-positive and gram-negative organisms. Cephapirin is more resistant to beta-lactamases than are the penicillins and so is effective against staphylococci, with the exception of methicillin-resistant staphylococci.
Cefa -ak Absorption
No information avaliable
Cefa -ak side effects and Toxicity
Rats exposed via the oral route to cephapirin displayed low acute toxicity (LD50 = 14000 mg/kg). The most common adverse reactions are hypersensitivity reactions and alterations to liver function. Evidence of white blood cell disorders and anaemia were noted in some subjects.
Cefa -ak Patient Information
No information avaliable
Cefa -ak Organisms Affected
Enteric bacteria and other eubacteria
