Carboquone
Category
Carboquone Brand names, Carboquone Analogs
Carboquone Brand Names Mixture
Carboquone Chemical_Formula
Cl2H4N2Pt
Carboquone RX_link
http://www.rxlist.com/cgi/generic3/cisplatin.htm
Carboquone fda sheet
Carboquone msds (material safety sheet)
Carboquone Synthesis Reference
No information avaliable
Carboquone Molecular Weight
298.029 g/mol
Carboquone Melting Point
270 oC
Carboquone H2O Solubility
2530 mg/L
Carboquone State
Solid
Carboquone LogP
-2.19
Carboquone Dosage Forms
Solution
Carboquone Indication
For the treatment of metastatic testicular tumors, metastatic ovarian tumors and advanced bladder cancer.
Carboquone Pharmacology
Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumor growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide. In addition, these drugs add methyl or other alkyl groups onto molecules where they do not belong which in turn inhibits their correct utilization by base pairing and causes a miscoding of DNA. Alkylating agents are cell cycle-nonspecific. Alkylating agents work by three different mechanisms all of which achieve the same end result - disruption of DNA function and cell death.
Carboquone Absorption
No information avaliable
Carboquone side effects and Toxicity
No information avaliable
Carboquone Patient Information
No information avaliable
Carboquone Organisms Affected
Humans and other mammals
