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Carac Brand names, Carac Analogs

Carac Brand Names Mixture

  • No information avaliable

Carac Chemical_Formula


Carac RX_link

Carac fda sheet

Carac FDA

Carac msds (material safety sheet)

Carac MSDS

Carac Synthesis Reference

Heidelberger et al., U.S. Pat 2802005(1956)

Carac Molecular Weight

130.077 g/mol

Carac Melting Point


Carac H2O Solubility

< 0.1 g/100 mL at 19 °C

Carac State


Carac LogP


Carac Dosage Forms

Topical preparations; Solution for injection

Carac Indication

For the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, rectum, breast, stomach and pancrease.

Carac Pharmacology

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.

Carac Absorption


Carac side effects and Toxicity

LD50=230mg/kg (orally in mice)

Carac Patient Information

Carac Organisms Affected

Humans and other mammals