PharmacyCodes



Butenafina [INN-Spanish] en es it fr

Butenafina [INN-Spanish] Brand names, Butenafina [INN-Spanish] Analogs

Butenafina [INN-Spanish] Brand Names Mixture

  • No information avaliable

Butenafina [INN-Spanish] Chemical_Formula

C23H27N

Butenafina [INN-Spanish] RX_link

http://www.rxlist.com/cgi/generic2/butenafine.htm

Butenafina [INN-Spanish] fda sheet

Butenafina_[INN-Spanish] FDA

Butenafina [INN-Spanish] msds (material safety sheet)

Butenafina [INN-Spanish] Synthesis Reference

No information avaliable

Butenafina [INN-Spanish] Molecular Weight

317.467 g/mol

Butenafina [INN-Spanish] Melting Point

No information avaliable

Butenafina [INN-Spanish] H2O Solubility

Slightly soluble (HCl salt)

Butenafina [INN-Spanish] State

Solid

Butenafina [INN-Spanish] LogP

7.12

Butenafina [INN-Spanish] Dosage Forms

Cream (10 mg drug per gram of cream)

Butenafina [INN-Spanish] Indication

For the topical treatment of the following dermatologic infections: tinea (pityriasis) versicolor due to M. furfur, interdigital tinea pedis (athlete’s foot), tinea corporis (ringworm) and tinea cruris (jock itch) due to E. floccosum, T. mentagrophytes, T. rubrum, and T. tonsurans.

Butenafina [INN-Spanish] Pharmacology

Butenafine is an antifungal agent that acts by inhibiting squalene epoxidase, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes. It is mainly active against dermatophytes and has superior fungicidal activity against this group of fungi when compared to that of terbinafine, naftifine, tolnaftate, clotrimazole, and bifonazole. It is active also against Candida albicans and this activity is superior to that of terbinafine and naftifine. Butenafine also generates low MICs for Cryptococcus neoformans and Aspergillus spp. as well.

Butenafina [INN-Spanish] Absorption

The total amount absorbed through the skin into the systemic circulation has not been quantified.

Butenafina [INN-Spanish] side effects and Toxicity

No information avaliable

Butenafina [INN-Spanish] Patient Information

Butenafina [INN-Spanish] Organisms Affected

Fungi