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Buprenex Brand names, Buprenex Analogs

Buprenex Brand Names Mixture

  • No information avaliable

Buprenex Chemical_Formula

C29H41NO4

Buprenex RX_link

http://www.rxlist.com/cgi/generic3/suboxone.htm

Buprenex fda sheet

Buprenex FDA

Buprenex msds (material safety sheet)

Buprenex Synthesis Reference

No information avaliable

Buprenex Molecular Weight

467.64 g/mol

Buprenex Melting Point

No information avaliable

Buprenex H2O Solubility

No information avaliable

Buprenex State

Solid

Buprenex LogP

5.096

Buprenex Dosage Forms

Tablet (sublingual)

Buprenex Indication

For the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence.

Buprenex Pharmacology

Buprenorphine is a synthetic opioid analgesic and thebaine derivative, with a longer duration of action than morphine. Buprenorphine interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, buprenorphine exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Buprenorphine may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Buprenorphine depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.

Buprenex Absorption

31% bioavailability (sublingual)

Buprenex side effects and Toxicity

Manifestations of acute overdose include pinpoint pupils, sedation, hypotension, respiratory depression and death.

Buprenex Patient Information

Buprenex Organisms Affected

Humans and other mammals