Bromoxidine
Bromoxidine Brand names, Bromoxidine Analogs
Bromoxidine Brand Names Mixture
- None
Bromoxidine Chemical_Formula
C11H10BrN5
Bromoxidine RX_link
http://www.rxlist.com/cgi/generic3/alphagan-p.htm
Bromoxidine fda sheet
Bromoxidine msds (material safety sheet)
Bromoxidine Synthesis Reference
M. B. Thomas, M. T. Williams, Ger. Pat. 2,538,630 (1976 to Pfizer)
Bromoxidine Molecular Weight
292.135 g/mol
Bromoxidine Melting Point
207.5 oC
Bromoxidine H2O Solubility
Soluble (1.5 mg/mL)
Bromoxidine State
Solid
Bromoxidine LogP
0.782
Bromoxidine Dosage Forms
0.2% solution
Bromoxidine Indication
For the lowering of intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Bromoxidine Pharmacology
Brimonidine significantly lowers intraocular pressure with minimal effects on cardiovascular and pulmonary parameters. It lowers intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow.
Bromoxidine Absorption
Minimal systemic absorption occurs after ocular insertion.
Bromoxidine side effects and Toxicity
Oral LD50 is 50 mg/kg in mice and 100 mg/kg in rats.
Bromoxidine Patient Information
PATIENT INFORMATION
Brimonidine tartrate is used for the treatment of open-angle glaucoma and ocular hypertension. Do not take this drug if you are currently taking MAO Inhibitors (e.g., Parnate). Inform your doctor if you are pregnant or nursing.
This product may stain soft contact lenses. Wait at least 15 minutes after instilling brimonidine to insert contact lenses.
May cause drowsiness or tiredness; use caution while driving or operating hazardous machinery. May cause dry mouth, blurring, stinging, or burning of the eyes; headaches, fatigue or drowsiness; allergic or itching of the eyes. Tell your doctor or pharmacist if these effects occur.
Brimonidine tartrate is used for the treatment of open-angle glaucoma and ocular hypertension. Do not take this drug if you are currently taking MAO Inhibitors (e.g., Parnate). Inform your doctor if you are pregnant or nursing.
This product may stain soft contact lenses. Wait at least 15 minutes after instilling brimonidine to insert contact lenses.
May cause drowsiness or tiredness; use caution while driving or operating hazardous machinery. May cause dry mouth, blurring, stinging, or burning of the eyes; headaches, fatigue or drowsiness; allergic or itching of the eyes. Tell your doctor or pharmacist if these effects occur.
Bromoxidine Organisms Affected
Humans and other mammals
