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Bleocin Brand names, Bleocin Analogs

Bleocin Brand Names Mixture

  • No information avaliable

Bleocin Chemical_Formula


Bleocin RX_link

Bleocin fda sheet

Bleocin msds (material safety sheet)

Bleocin MSDS

Bleocin Synthesis Reference

T. Takita et al., ibid. 254

Bleocin Molecular Weight

1415.56 g/mol

Bleocin Melting Point

71 oC

Bleocin H2O Solubility


Bleocin State


Bleocin LogP

No information avaliable

Bleocin Dosage Forms

Injection; Powder for solution

Bleocin Indication

For palliative treatment in the management malignant neoplasm (trachea, bronchus, lung), squamous cell carcinoma, and lymphomas.

Bleocin Pharmacology

Bleomycin is an antibiotic which has been shown to have antitumor activity. Bleomycin selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of mitomycin-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed. Bleomycin has been shown in vitro to inhibit B cell, T cell, and macrophage proliferation and impair antigen presentation, as well as the secretion of interferon gamma, TNFa, and IL-2. The antibiotic antitumor drugs are cell cycle-nonspecific except for Bleomycin (which has major effects in G2 and M phases).

Bleocin Absorption

Systemic absorption is approximately 45%.

Bleocin side effects and Toxicity

Excessive exposure may cause fever, chills, nausea, vomiting, mental, confusion, and wheezing. Bleomycin may cause irritation to eyes, skin and respiratory tract. It may also cause a darkening or thickening of the skin. It may cause an allergic reaction.

Bleocin Patient Information

Bleomycin should only be administered under the supervision of a qualified
healthcare provider experienced in the use of cancer chemotherapeutic agents.
Serious side effects have been reported with the use of bleomycin including: allergic
reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue,
or face; or hives); a severe reaction consisting of low blood pressure, mental confusion,
fever, chills, and wheezing; pulmonary fibrosis (a lung condition); and others. Talk to
your doctor about the possible side effects from treatment with bleomycin.

Bleocin Organisms Affected

Humans and other mammals