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Bivalirudin Brand names, Bivalirudin Analogs

Bivalirudin Brand Names Mixture

  • Tavist-D Tablets (Clemastine + Phenylpropanolamine Hydrochloride)

Bivalirudin Chemical_Formula

C98H138N24O33

Bivalirudin RX_link

http://www.rxlist.com/cgi/generic/angiomax.htm

Bivalirudin fda sheet

Bivalirudin FDA

Bivalirudin msds (material safety sheet)

Bivalirudin Synthesis Reference

No information avaliable

Bivalirudin Molecular Weight

2180.3

Bivalirudin Melting Point

No information avaliable

Bivalirudin H2O Solubility

No information avaliable

Bivalirudin State

Liquid

Bivalirudin LogP

-0.985

Bivalirudin Dosage Forms

Solution (IV Injection and Infusion)

Bivalirudin Indication

For treatment of heparin-induced thrombocytopenia

Bivalirudin Pharmacology

Angiomax directly inhibits thrombin by specifically binding both to the catalytic site and to the anion-binding exosite of circulating and clot-bound thrombin. Thrombin is a serine proteinase that plays a central role in the thrombotic process, acting to cleave fibrinogen into fibrin monomers and to activate Factor XIII to Factor XIIIa, allowing fibrin to develop a covalently cross-linked framework which stabilizes the thrombus; thrombin also activates Factors V and VIII, promoting further thrombin generation, and activates platelets, stimulating aggregation and granule release

Bivalirudin Absorption

No information avaliable

Bivalirudin side effects and Toxicity

No information avaliable

Bivalirudin Patient Information

No information avaliable

Bivalirudin Organisms Affected

Humans and other mammals