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Biperidine
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Biperidine Brand names, Biperidine Analogs

Biperidine Brand Names Mixture

  • No information avaliable

Biperidine Chemical_Formula

C21H29NO

Biperidine RX_link

http://www.rxlist.com/cgi/generic2/biperiden.htm

Biperidine fda sheet

Biperidine msds (material safety sheet)

Biperidine Synthesis Reference

No information avaliable

Biperidine Molecular Weight

311.461 g/mol

Biperidine Melting Point

114 oC

Biperidine H2O Solubility

25.1 mg/L

Biperidine State

Solid

Biperidine LogP

3.85

Biperidine Dosage Forms

Tablet

Biperidine Indication

For use as an adjunct in the therapy of all forms of parkinsonism and control of extrapyramidal disorders secondary to neuroleptic drug therapy.

Biperidine Pharmacology

Biperiden is a weak peripheral anticholinergic agent. It has, therefore, some antisecretory, antispasmodic and mydriatic effects. In addition, biperiden possesses nicotinolytic activity. The parenteral form of biperiden is an effective and reliable agent for the treatment of acute episodes of extrapyramidal disturbances sometimes seen during treatment with neuroleptic agents. Akathisia, akinesia, dyskinetic tremors, rigor, oculogyric crisis, spasmodic torticollis, and profuse sweating are markedly reduced or eliminated. With parenteral biperiden, these drug-induced disturbances are rapidly brought under control.

Biperidine Absorption

87% bioavailability

Biperidine side effects and Toxicity

LD50=760 mg/kg (Orally in rats). Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Biperidine Patient Information

No information avaliable

Biperidine Organisms Affected

Humans and other mammals