Biperiden Hydrochloride
Category
Biperiden Hydrochloride Brand names, Biperiden Hydrochloride Analogs
Biperiden Hydrochloride Brand Names Mixture
Biperiden Hydrochloride Chemical_Formula
C21H29NO
Biperiden Hydrochloride RX_link
http://www.rxlist.com/cgi/generic2/biperiden.htm
Biperiden Hydrochloride fda sheet
Biperiden Hydrochloride msds (material safety sheet)
Biperiden Hydrochloride Synthesis Reference
No information avaliable
Biperiden Hydrochloride Molecular Weight
311.461 g/mol
Biperiden Hydrochloride Melting Point
114 oC
Biperiden Hydrochloride H2O Solubility
25.1 mg/L
Biperiden Hydrochloride State
Solid
Biperiden Hydrochloride LogP
3.85
Biperiden Hydrochloride Dosage Forms
Tablet
Biperiden Hydrochloride Indication
For use as an adjunct in the therapy of all forms of parkinsonism and control of extrapyramidal disorders secondary to neuroleptic drug therapy.
Biperiden Hydrochloride Pharmacology
Biperiden is a weak peripheral anticholinergic agent. It has, therefore, some antisecretory, antispasmodic and mydriatic effects. In addition, biperiden possesses nicotinolytic activity. The parenteral form of biperiden is an effective and reliable agent for the treatment of acute episodes of extrapyramidal disturbances sometimes seen during treatment with neuroleptic agents. Akathisia, akinesia, dyskinetic tremors, rigor, oculogyric crisis, spasmodic torticollis, and profuse sweating are markedly reduced or eliminated. With parenteral biperiden, these drug-induced disturbances are rapidly brought under control.
Biperiden Hydrochloride Absorption
87% bioavailability
Biperiden Hydrochloride side effects and Toxicity
LD50=760 mg/kg (Orally in rats). Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Biperiden Hydrochloride Patient Information
No information avaliable
Biperiden Hydrochloride Organisms Affected
Humans and other mammals
