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Biocoryl Brand names, Biocoryl Analogs

Biocoryl Brand Names Mixture

  • No information avaliable

Biocoryl Chemical_Formula

C13H21N3O

Biocoryl RX_link

http://www.rxlist.com/cgi/generic3/procain.htm

Biocoryl fda sheet

Biocoryl msds (material safety sheet)

Biocoryl MSDS

Biocoryl Synthesis Reference

Shannon SK et al., J Comb Chem. 2003 Nov-Dec;5(6):860-8

Biocoryl Molecular Weight

235.325 g/mol

Biocoryl Melting Point

165-169 oC

Biocoryl H2O Solubility

5050 mg/L

Biocoryl State

Solid

Biocoryl LogP

1.282

Biocoryl Dosage Forms

Capsule; Liquid; Solution; Tablet (extended-release)

Biocoryl Indication

For the treatment of life-threatening ventricular arrhythmias.

Biocoryl Pharmacology

Procainamide is an agent indicated for production of local or regional anesthesia and in the treatment of ventricular tachycardia occurring during cardiac manipulation, such as surgery or catheterization, or which may occur during acute myocardial infarction, digitalis toxicity, or other cardiac diseases. The mode of action of the antiarrhythmic effect of Procainamide appears to be similar to that of procaine and quinidine. Ventricular excitability is depressed and the stimulation threshold of the ventricle is increased during diastole. The sinoatrial node is, however, unaffected.

Biocoryl Absorption

75 to 95%

Biocoryl side effects and Toxicity

LD50=95 mg/kg (rat, IV); LD50=312 mg/kg (mouse, oral); LD50=103 mg/kg (mouse, IV); LD50=250 mg/kg (rabbit, IV)

Biocoryl Patient Information

The patient should be encouraged to disclose any past history of drug sensitivity, especially to procaine or other local anesthetic agents, or aspirin, and to report any history of kidney disease, congestive heart failure, myasthenia gravis, liver disease or lupus erythematosus.

The patient should be counseled to report any symptoms of arthralgia, myalgia, fever, chills, skin rash, easy bruising, sore throat or sore mouth, infections, dark urine or icterus, wheezing, muscular weakness, chest or abdominal pain, palpitations, nausea, vomiting, anorexia, diarrhea, hallucinations, dizziness or depression.

Biocoryl Organisms Affected

Humans and other mammals