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Benzylpenicillin_G
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Benzylpenicillin G Brand names, Benzylpenicillin G Analogs

Benzylpenicillin G Brand Names Mixture

  • No information avaliable

Benzylpenicillin G Chemical_Formula

C16H18N2O4S

Benzylpenicillin G RX_link

http://www.rxlist.com/cgi/generic3/pengk.htm

Benzylpenicillin G fda sheet

Benzylpenicillin G msds (material safety sheet)

Benzylpenicillin_G MSDS

Benzylpenicillin G Synthesis Reference

No information avaliable

Benzylpenicillin G Molecular Weight

334.391 g/mol

Benzylpenicillin G Melting Point

214-217oC

Benzylpenicillin G H2O Solubility

Slightly soluble (210 mg/L)

Benzylpenicillin G State

Solid

Benzylpenicillin G LogP

1.212

Benzylpenicillin G Dosage Forms

Powder for solution; Suspension; Tablet

Benzylpenicillin G Indication

For use in the treatment of severe infections caused by penicillin G-susceptible microorganisms when rapid and high penicillin levels are required.

Benzylpenicillin G Pharmacology

Penicillin G is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Penicillin G has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of penicillin G results from the inhibition of cell wall synthesis and is mediated through penicillin G binding to penicillin binding proteins (PBPs). Penicillin G is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.

Benzylpenicillin G Absorption

Rapidly absorbed following both intramuscular and subcutaneous injection. Initial blood levels following parenteral administration are high but transient.

Benzylpenicillin G side effects and Toxicity

Oral LD50 in rat is 8900 mk/kg. Neurological adverse reactions, including convulsions, may occur with the attainment of high CSF levels of beta-lactams.

Benzylpenicillin G Patient Information

No information avaliable

Benzylpenicillin G Organisms Affected

Enteric bacteria and other eubacteria