Benzthazide
Benzthazide Brand names, Benzthazide Analogs
Benzthazide Brand Names Mixture
- No information avaliable
Benzthazide Chemical_Formula
C15H14ClN3O4S3
Benzthazide RX_link
No information avaliable
Benzthazide fda sheet
Benzthazide msds (material safety sheet)
Benzthazide Synthesis Reference
No information avaliable
Benzthazide Molecular Weight
431.94 g/mol
Benzthazide Melting Point
231.5 oC
Benzthazide H2O Solubility
8.91 mg/L
Benzthazide State
Solid
Benzthazide LogP
2.918
Benzthazide Dosage Forms
Tablet
Benzthazide Indication
For the treatment of high blood pressure and management of edema.
Benzthazide Pharmacology
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Benzthazide Absorption
Absorbed in the digestive tract.
Benzthazide side effects and Toxicity
Symptoms of overdose include nausea, vomiting, fatigue, urinary problems and drowsiness.
Benzthazide Patient Information
Benzthazide Organisms Affected
Humans and other mammals
