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Basofortina Brand names, Basofortina Analogs

Basofortina Brand Names Mixture

  • No information avaliable

Basofortina Chemical_Formula


Basofortina RX_link

Basofortina fda sheet

Basofortina msds (material safety sheet)

Basofortina MSDS

Basofortina Synthesis Reference

A. Stoll et al., eidem, Helv. Chim. Acta. 26, 944 (1943)

Basofortina Molecular Weight

339.432 g/mol

Basofortina Melting Point

172 oC

Basofortina H2O Solubility

25 mg/mL

Basofortina State


Basofortina LogP


Basofortina Dosage Forms

Injection (intramuscular or intravenous); Tablet

Basofortina Indication

For the prevention and control of excessive bleeding following vaginal childbirth

Basofortina Pharmacology

Methylergonovine is a semisynthetic ergot alkaloid and a derivative of ergonovine and is used for the prevention and control of postpartum and post-abortion hemorrhage. In general, the effects of all the ergot alkaloids appear to results from their actions as partial agonists or antagonists at adrenergic, dopaminergic, and tryptaminergic receptors. The spectrum of effects depends on the agent, dosage, species, tissue, and experimental or physiological conditions. All of the alkaloids of ergot significantly increase the motor activity of the uterus. After small doses contractions are increased in force or frequency, or both, but are followed by a normal degree of relaxation. As the dose is increased, contractions become more forceful and prolonged, resting tonus is markedly increased, and sustained contracture can result.

Basofortina Absorption

Absorption is rapid after oral (60% bioavailability) and intramuscular (78% bioavailability) administration.

Basofortina side effects and Toxicity

Signs and symptoms of overexposure: hypertension, seizures, headache, hypotension, nausea, and vomiting.

Basofortina Patient Information

Basofortina Organisms Affected

Humans and other mammals