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Arumel Brand names, Arumel Analogs

Arumel Brand Names Mixture

  • No information avaliable

Arumel Chemical_Formula


Arumel RX_link

Arumel fda sheet

Arumel FDA

Arumel msds (material safety sheet)

Arumel MSDS

Arumel Synthesis Reference

Heidelberger et al., U.S. Pat 2802005(1956)

Arumel Molecular Weight

130.077 g/mol

Arumel Melting Point


Arumel H2O Solubility

< 0.1 g/100 mL at 19 °C

Arumel State


Arumel LogP


Arumel Dosage Forms

Topical preparations; Solution for injection

Arumel Indication

For the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, rectum, breast, stomach and pancrease.

Arumel Pharmacology

Fluorouracil is an antineoplastic anti-metabolite. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division. Fluorouracil blocks an enzyme which converts the cytosine nucleotide into the deoxy derivative. In addition, DNA synthesis is further inhibited because Fluorouracil blocks the incorporation of the thymidine nucleotide into the DNA strand.

Arumel Absorption


Arumel side effects and Toxicity

LD50=230mg/kg (orally in mice)

Arumel Patient Information

Arumel Organisms Affected

Humans and other mammals