Apomorphine
Category
Apomorphine Brand names, Apomorphine Analogs
Apomorphine Brand Names Mixture
Homeopathic Remedy Thc No. 48 Dps (Antimony Trisulfide + Apomorphine + Ipecac + Phosphorus + Pulsatilla)
Apomorphine Chemical_Formula
C17H17NO2
Apomorphine RX_link
http://www.rxlist.com/cgi/generic3/apokyn.htm
Apomorphine fda sheet
Apomorphine msds (material safety sheet)
Apomorphine Synthesis Reference
J. L. Neumeyer et al., J. Pharm. Sci. 59, 1850 (1970);
Apomorphine Molecular Weight
267.322 g/mol
Apomorphine Melting Point
No information avaliable
Apomorphine H2O Solubility
1.66E+004 mg/L
Apomorphine State
Solid
Apomorphine LogP
3.03
Apomorphine Dosage Forms
Subcutaneous solution (not for IV)
Apomorphine Indication
For the acute, intermittent treatment of hypomobility, off episodes (end-of-dose wearing off and unpredictable on/off episodes) associated with advanced Parkinson's disease.
Apomorphine Pharmacology
Apomorphine is a type of dopaminergic agonist, a morphine derivative which primarily affects the hypothalamic region of the brain. Drugs containing this substance are sometimes used in the treatment of Parkinson's disease or erectile dysfunction. In higher doses it is a highly effective emetic.
Apomorphine Absorption
100% following subcutaneous administration
Apomorphine Toxicity
LD50=0.6 mmoles/kg (mice, intraperitoneal)
Apomorphine Patient Information
Apomorphine Organisms Affected
Humans and other mammals
