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Apo-Methyldopa Brand names, Apo-Methyldopa Analogs

Apo-Methyldopa Brand Names Mixture

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Apo-Methyldopa Chemical_Formula


Apo-Methyldopa RX_link


Apo-Methyldopa fda sheet

Apo-Methyldopa FDA

Apo-Methyldopa msds (material safety sheet)

Apo-Methyldopa MSDS

Apo-Methyldopa Synthesis Reference

No information avaliable

Apo-Methyldopa Molecular Weight

1270.28 g/mol

Apo-Methyldopa Melting Point

No information avaliable

Apo-Methyldopa H2O Solubility

Freely soluble as sodium salt (> 200mg/mL)

Apo-Methyldopa State


Apo-Methyldopa LogP

No information avaliable

Apo-Methyldopa Dosage Forms

Powder for solution (for injection)

Apo-Methyldopa Indication

For use in the treatment of patients with esophageal candidiasis and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation.

Apo-Methyldopa Pharmacology

Formerly known as FK463, micafungin is a novel antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class. The U.S. Food and Drug Administration approved micafungin in March 2005. Micafungin inhibits an enzyme essential for fungal cell-wall synthesis and is fungicidal (lethal) for Candida. Micafungin can be used concomitantly with a variety of other drugs, including the HIV protease inhibitor ritonavir and the transplant medications cyclosporine and tacrolimus.

Apo-Methyldopa Absorption

No information avaliable

Apo-Methyldopa side effects and Toxicity

Intravenous LD50 in rats is 125mg/kg. In dogs it is >200mg/kg. No cases of overdosage have been reported. Repeated daily doses up to 8 mg/kg (maximum total dose of 896 mg) in adult patients have been administered in clinical trials with no reported dose-limiting toxicity. The minimum lethal dose is 125 mg/kg in rats, equivalent to 8.1 times the recommended human clinical dose for esophageal candidiasis based on body surface area comparisons.

Apo-Methyldopa Patient Information

No information avaliable

Apo-Methyldopa Organisms Affected

Aspergillis, Candida and other fungi