Amsacrine
Amsacrine Brand names, Amsacrine Analogs
Amsacrine Brand Names Mixture
- No information avaliable
Amsacrine Chemical_Formula
C21H19N3O3S
Amsacrine RX_link
No information avaliable
Amsacrine fda sheet
Amsacrine msds (material safety sheet)
Amsacrine Synthesis Reference
No information avaliable
Amsacrine Molecular Weight
393.46 g/mol
Amsacrine Melting Point
234-236oC
Amsacrine H2O Solubility
<1 mg/mL
Amsacrine State
Solid
Amsacrine LogP
5.273
Amsacrine Dosage Forms
Liquid
Amsacrine Indication
For treatment of acute myeloid leukaemia.
Amsacrine Pharmacology
Amsacrine is an aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects.
Amsacrine Absorption
Poorly absorbed
Amsacrine side effects and Toxicity
Symptoms of overdose include nausea and vomiting, diarrhea, some cardiotoxicity (rarely).
Amsacrine Patient Information
No information avaliable
Amsacrine Organisms Affected
Humans and other mammals
