Amoxycillin Trihydrate

• Anti-bacterial Agents
• Penicillins
• ATC:J01CA04

• AMC
• AMPC
• Actimoxi
• Amoclen
• Amolin
• Amopen
• Amopenixin
• Amoxi
• Amoxi-Mast
• Amoxibiotic
• Amoxicilina [INN-Spanish]
• Amoxicillin (USAN)
• Amoxicillin Trihydrate
• Amoxicillin anhydrous
• Amoxicilline [INN-French]
• Amoxicillinum [INN-Latin]
• Amoxiden
• Amoxil
• Amoxivet
• Amoxycillin
• Amoxycillin Trihydrate
• Ampy-Penyl
• Anemolin
• Aspenil
• Biomox
• Bristamox
• Cemoxin
• Clamoxyl
• D-Amoxicillin
• Delacillin
• Dispermox
• Efpenix
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• Ibiamox
• Imacillin
• Lamoxy
• Metafarma capsules
• Metifarma capsules
• Moxacin
• Moxal
• Ospamox
• Pamoxicillin
• Piramox
• Polymox
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• Sawamox PM
• Sumox
• Tolodina
• Trimox
• Unicillin
• Utimox
• Vetramox
• Wymox
• Zimox
• p-Hydroxyampicillin

• Co-amoxiclav (amoxicillin + clavulanic acid)
• Augmentin (amoxicillin + clavulanic acid)
• Prevpac (amoxicillin + clarithromycin + lansoprazole)

C₁₆H₁₉N₃O₅S

http://www.rxlist.com/cgi/generic/amox.htm

Amoxycillin_Trihydrate FDA

Amoxycillin_Trihydrate MSDS

Nayler, Smith, U.S. Pat. 3,192,198 (1965)

365.405 g/mol

194 ^oC

3430 mg/L

Solid

-0.124

Capsule (250 mg or 500 mg); Powder for solution; Powder for suspension; Suspension; Tablet (500 mg or 875 mg)

For the treatment of infections of the ear, nose, and throat, the genitourinary tract, the skin and skin structure, and the lower respiratory tract due to susceptible (only b-lactamase-negative) strains of Streptococcus spp. (a- and b-hemolytic strains only), S. pneumoniae, Staphylococcus spp., H. influenzae, E. coli, P. mirabilis, or E. faecalis. Also for the treatment of acute, uncomplicated gonorrhea (ano-genital and urethral infections) due to N. gonorrhoeae (males and females).

Amoxicillin is a moderate-spectrum antibiotic active against a wide range of Gram-positive, and a limited range of Gram-negative organisms. It is usually the drug of choice within the class because it is better absorbed, following oral administration, than other beta-lactam antibiotics. Amoxicillin is susceptible to degradation by β-lactamase-producing bacteria, and so may be given with clavulanic acid to increase its susceptability. The incidence of β-lactamase-producing resistant organisms, including E. coli, appears to be increasing. Amoxicillin is sometimes combined with clavulanic acid, a β-lactamase inhibitor, to increase the spectrum of action against Gram-negative organisms, and to overcome bacterial antibiotic resistance mediated through β-lactamase production.

Rapidly absorbed after oral administration.

Serious toxicity is unlikely following large doses of amoxicillin. Acute ingestion of large doses of amoxicillin may cause nausea, vomiting, diarrhea and abdominal pain. Acute oliguric renal failure and hematuria may occur following large doses.

Amoxicillin is an antibiotic for treatment of infection.
Take at regular intervals, around the clock. Always finish course of therapy.
Take with or without meals.
May cause serious allergic reactions in those with penicillin allergy.
May cause nausea, vomiting and diarrhea; notify your doctor or pharmacist if these occur.

Enteric bacteria and other eubacteria