Amlodis
Amlodis Brand names, Amlodis Analogs
Amlodis Brand Names Mixture
- Lotrel (amlodipine + benazepril)
Amlodis Chemical_Formula
C20H25ClN2O5
Amlodis RX_link
http://www.rxlist.com/cgi/generic/amlod2.htm
Amlodis fda sheet
Amlodis msds (material safety sheet)
Amlodis Synthesis Reference
S. F. Campbell et al., U.S. Pat. 4,572,909 (1986)
Amlodis Molecular Weight
408.876 g/mol
Amlodis Melting Point
178-179oC
Amlodis H2O Solubility
75.3 mg/L
Amlodis State
Solid
Amlodis LogP
2.347
Amlodis Dosage Forms
Tablets (equivalent to 2.5, 5 and 10 mg)
Amlodis Indication
For the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Amlodis Pharmacology
Amlodipine, a calcium-channel blocker, is used alone or with benazepril, an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Amlodipine is similar to the peripheral vasodilator nifedipine and other members of the dihydropyridine class.
Amlodis Absorption
Amlodipine is slowly and almost completely absorbed from the gastrointestinal tract.
Amlodis side effects and Toxicity
Gross overdosage could result in excessive peripheral vasodilatation and possibly reflex tachycardia. Marked and probably prolonged systemic hypotension up to an including shock with fatal outcome have been reported.
Amlodis Patient Information
Amlodis Organisms Affected
Humans and other mammals
