Aminocaproic Acid en es it fr

Aminocaproic Acid Brand names, Aminocaproic Acid Analogs

Aminocaproic Acid Brand Names Mixture

  • No information avaliable

Aminocaproic Acid Chemical_Formula

C6H13NO2

Aminocaproic Acid RX_link

http://www.rxlist.com/cgi/generic/amicarpre.htm

Aminocaproic Acid fda sheet

Aminocaproic_Acid FDA

Aminocaproic Acid msds (material safety sheet)

Aminocaproic_Acid MSDS

Aminocaproic Acid Synthesis Reference

No information avaliable

Aminocaproic Acid Molecular Weight

131.173 g/mol

Aminocaproic Acid Melting Point

205 oC

Aminocaproic Acid H2O Solubility

5.05E+005 mg/L

Aminocaproic Acid State

Solid

Aminocaproic Acid LogP

0.306

Aminocaproic Acid Dosage Forms

Solution for injection (containing 250 mg/mL of aminocaproic acid) and tablets (500, 1000mg)

Aminocaproic Acid Indication

For use in the treatment of excessive postoperative bleeding.

Aminocaproic Acid Pharmacology

Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. The fibrinolysis-inhibitory effects of aminocaproic acid appear to be exerted principally via inhibition of plasminogen activators and to a lesser degree through antiplasmin activity.

Aminocaproic Acid Absorption

Absorbed rapidly following oral administration. In adults, oral absorption appears to be a zero-order process with an absorption rate of 5.2 g/hr. The mean lag time in absorption is 10 minutes. After a single oral dose of 5 g, absorption was complete (F=1).

Aminocaproic Acid side effects and Toxicity

A few cases of acute overdosage with intravenous administration have been reported. The effects have ranged from no reaction to transient hypotension to severe acute renal failure leading to death. The intravenous and oral LD50 were 3.0 and 12.0 g/kg respectively in the mouse and 3.2 and 16.4 g/kg respectively in the rat. An intravenous infusion dose of 2.3 g/kg was lethal in the dog.

Aminocaproic Acid Patient Information

Aminocaproic Acid Organisms Affected

Humans and other mammals