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Amikapron Brand names, Amikapron Analogs

Amikapron Brand Names Mixture

  • No information avaliable

Amikapron Chemical_Formula

C21H28N2O5

Amikapron RX_link

http://www.rxlist.com/cgi/generic3/trimethbenz.htm

Amikapron fda sheet

Amikapron FDA

Amikapron msds (material safety sheet)

Amikapron MSDS

Amikapron Synthesis Reference

No information avaliable

Amikapron Molecular Weight

388.458 g/mol

Amikapron Melting Point

188.7 oC

Amikapron H2O Solubility

40 mg/L

Amikapron State

Solid

Amikapron LogP

2.784

Amikapron Dosage Forms

Capsules (300 mg) for oral administration; Suppositories (200 mg); Injectable (100 mg, 200 mg)

Amikapron Indication

For the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.

Amikapron Pharmacology

Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.

Amikapron Absorption

The relative bioavailability of the capsule formulation compared to the solution is 100%.

Amikapron side effects and Toxicity

Oral LD50 in mice is 1600 mg/kg.

Amikapron Patient Information

No information avaliable

Amikapron Organisms Affected

Humans and other mammals