Amidate
Amidate Brand names, Amidate Analogs
Amidate Brand Names Mixture
- No information avaliable
Amidate Chemical_Formula
C15H14FN3O3
Amidate RX_link
http://www.rxlist.com/cgi/generic3/flumazenil.htm
Amidate fda sheet
Amidate msds (material safety sheet)
Amidate Synthesis Reference
No information avaliable
Amidate Molecular Weight
303.288 g/mol
Amidate Melting Point
201-203 oC
Amidate H2O Solubility
128 mg/L
Amidate State
Solid
Amidate LogP
1.468
Amidate Dosage Forms
Solution for injection (0.1 mg/mL)
Amidate Indication
For the complete or partial reversal of the sedative effects of benzodiazepines in cases where general anesthesia has been induced and/or maintained with benzodiazepines, where sedation has been produced with benzodiazepines for diagnostic and therapeutic procedures, and for the management of benzodiazepine overdose.
Amidate Pharmacology
Flumazenil does not antagonize the central nervous system effects of drugs affecting GABA-ergic neurons by means other than the benzodiazepine receptor (including ethanol, barbiturates, or general anesthetics) and does not reverse the effects of opioids.
Amidate Absorption
No information avaliable
Amidate side effects and Toxicity
In clinical studies, most adverse reactions to flumazenil were an extension of the pharmacologic effects of the drug in reversing benzodiazepine effects.
Amidate Patient Information
Amidate Organisms Affected
Humans and other mammals
