Amdinocillin en es it fr

Amdinocillin Brand names, Amdinocillin Analogs

Amdinocillin Brand Names Mixture

  • No information avaliable

Amdinocillin Chemical_Formula

C21H33N3O5S

Amdinocillin RX_link

No information avaliable

Amdinocillin fda sheet

Amdinocillin msds (material safety sheet)

Amdinocillin MSDS

Amdinocillin Synthesis Reference

No information avaliable

Amdinocillin Molecular Weight

439.57 g/mol

Amdinocillin Melting Point

156 oC

Amdinocillin H2O Solubility

Insoluble

Amdinocillin State

Solid

Amdinocillin LogP

3.09

Amdinocillin Dosage Forms

Injection

Amdinocillin Indication

Used in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species.

Amdinocillin Pharmacology

Amdinocillin is a novel, semisynthetic penicillin effective against many gram-negative bacteria. The antibacterial activity of amdinocillin is derived from its ability to bind specifically and avidly to Penicillin Binding Protein-2 (PBP 2). Amdinocillin is active alone against many gram-negative organisms. Pseudomonas and non-fermenting gram-negative bacteria, however, are usually resistant. Amdinocillin, in combination with many beta-lactams, exhibits marked synergy against many enterobacteriaceae. No such synergy can be demonstrated for gram-positive organisms or pseudomonas species. Amdinocillin is not beta-lactamase stable. Organisms which produce high levels of plasma-mediated beta-lactamase are resistant to the drug. Co-administration of probenecid results in markedly elevated plasma levels of amdinocillin and delays its excretion.

Amdinocillin Absorption

Poorly absorbed if given orally.

Amdinocillin side effects and Toxicity

No information avaliable

Amdinocillin Patient Information

Amdinocillin Organisms Affected

Gram-negative Bacteria