Alphagan
Alphagan Brand names, Alphagan Analogs
Alphagan Brand Names Mixture
- None
Alphagan Chemical_Formula
C11H10BrN5
Alphagan RX_link
http://www.rxlist.com/cgi/generic3/alphagan-p.htm
Alphagan fda sheet
Alphagan msds (material safety sheet)
Alphagan Synthesis Reference
M. B. Thomas, M. T. Williams, Ger. Pat. 2,538,630 (1976 to Pfizer)
Alphagan Molecular Weight
292.135 g/mol
Alphagan Melting Point
207.5 oC
Alphagan H2O Solubility
Soluble (1.5 mg/mL)
Alphagan State
Solid
Alphagan LogP
0.782
Alphagan Dosage Forms
0.2% solution
Alphagan Indication
For the lowering of intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Alphagan Pharmacology
Brimonidine significantly lowers intraocular pressure with minimal effects on cardiovascular and pulmonary parameters. It lowers intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow.
Alphagan Absorption
Minimal systemic absorption occurs after ocular insertion.
Alphagan side effects and Toxicity
Oral LD50 is 50 mg/kg in mice and 100 mg/kg in rats.
Alphagan Patient Information
PATIENT INFORMATION
Brimonidine tartrate is used for the treatment of open-angle glaucoma and ocular hypertension. Do not take this drug if you are currently taking MAO Inhibitors (e.g., Parnate). Inform your doctor if you are pregnant or nursing.
This product may stain soft contact lenses. Wait at least 15 minutes after instilling brimonidine to insert contact lenses.
May cause drowsiness or tiredness; use caution while driving or operating hazardous machinery. May cause dry mouth, blurring, stinging, or burning of the eyes; headaches, fatigue or drowsiness; allergic or itching of the eyes. Tell your doctor or pharmacist if these effects occur.
Brimonidine tartrate is used for the treatment of open-angle glaucoma and ocular hypertension. Do not take this drug if you are currently taking MAO Inhibitors (e.g., Parnate). Inform your doctor if you are pregnant or nursing.
This product may stain soft contact lenses. Wait at least 15 minutes after instilling brimonidine to insert contact lenses.
May cause drowsiness or tiredness; use caution while driving or operating hazardous machinery. May cause dry mouth, blurring, stinging, or burning of the eyes; headaches, fatigue or drowsiness; allergic or itching of the eyes. Tell your doctor or pharmacist if these effects occur.
Alphagan Organisms Affected
Humans and other mammals
