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Alendros Brand names, Alendros Analogs

Alendros Brand Names Mixture

  • No information avaliable

Alendros Chemical_Formula

C4H13NO7P2

Alendros RX_link

http://www.rxlist.com/cgi/generic/alendron.htm

Alendros fda sheet

Alendros FDA

Alendros msds (material safety sheet)

Alendros MSDS

Alendros Synthesis Reference

M. I. Kabachnik et al., Bull. Acad. Sci. USSR,.27, 374 (1978)

Alendros Molecular Weight

249.096 g/mol

Alendros Melting Point

233 - 235 oC

Alendros H2O Solubility

1mg/L

Alendros State

Solid

Alendros LogP

-3.198

Alendros Dosage Forms

Tablets (6.53, 13.05, 45.68, 52.21 or 91.37 mg of alendronate monosodium salt trihydrate)

Alendros Indication

For the treatment and prevention of osteoporosis in women and Paget's disease of bone in both men and women.

Alendros Pharmacology

Alendronate, a second-generation bisphosphonate is the first member of a group of drugs which strengthens bone. Alendronate is used to reduce hypercalcemia in tumor-induced bone disease, to treat corticosteroid-induced osteoporosis and Paget's disease, and to prevent osteoporosis in postmenopausal women.

Alendros Absorption

Relative to an intravenous (IV) reference dose, the mean oral bioavailability of alendronate in women was 0.7% for doses ranging from 5 to 40 mg when administered after an overnight fast and two hours before a standardized breakfast. Oral bioavailability of the 10 mg tablet in men (0.59%) was similar to that in women (0.78%) when administered after an overnight fast and 2 hours before breakfast.

Alendros side effects and Toxicity

Alendronate can damage the esophagus both by toxicity from the medication itself and by nonspecific irritation secondary to contact between the pill and the esophageal mucosa, similar to other cases of "pill esophagitis."

Alendros Patient Information

Alendros Organisms Affected

Humans and other mammals