Aldoril D50
Aldoril D50 Brand names, Aldoril D50 Analogs
- AMD
- Aldoclor-150
- Aldoclor-250
- Aldomet
- Aldometil
- Aldomin
- Aldoril 15
- Aldoril 25
- Aldoril D30
- Aldoril D50
- Alpha medopa
- Alphamethyldopa
- Apo-Methyldopa
- Bayer 1440 L
- Baypresol
- Becanta
- Dopamet
- Dopamethyperpax
- Dopatec
- Dopegyt
- Grospisk
- Hyperpax
- Hypolag
- L-Methyl Dopa
- Medomet
- Medopa
- Medopal
- Medopren
- Methoplain
- Methyldopa anhydrous
- Methyldopate
- Methyldopate HCL
- Mk. b51
- Novomedopa
- Nu-Medopa
- Presinol
- Presolisin
- Sedometil
- Sembrina
Aldoril D50 Brand Names Mixture
- No information avaliable
Aldoril D50 Chemical_Formula
C56H71N9O23S
Aldoril D50 RX_link
http://www.rxlist.com/cgi/generic4/mycamine.htm
Aldoril D50 fda sheet
Aldoril D50 msds (material safety sheet)
Aldoril D50 Synthesis Reference
No information avaliable
Aldoril D50 Molecular Weight
1270.28 g/mol
Aldoril D50 Melting Point
No information avaliable
Aldoril D50 H2O Solubility
Freely soluble as sodium salt (> 200mg/mL)
Aldoril D50 State
Solid
Aldoril D50 LogP
No information avaliable
Aldoril D50 Dosage Forms
Powder for solution (for injection)
Aldoril D50 Indication
For use in the treatment of patients with esophageal candidiasis and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation.
Aldoril D50 Pharmacology
Formerly known as FK463, micafungin is a novel antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class. The U.S. Food and Drug Administration approved micafungin in March 2005. Micafungin inhibits an enzyme essential for fungal cell-wall synthesis and is fungicidal (lethal) for Candida. Micafungin can be used concomitantly with a variety of other drugs, including the HIV protease inhibitor ritonavir and the transplant medications cyclosporine and tacrolimus.
Aldoril D50 Absorption
No information avaliable
Aldoril D50 side effects and Toxicity
Intravenous LD50 in rats is 125mg/kg. In dogs it is >200mg/kg. No cases of overdosage have been reported. Repeated daily doses up to 8 mg/kg (maximum total dose of 896 mg) in adult patients have been administered in clinical trials with no reported dose-limiting toxicity. The minimum lethal dose is 125 mg/kg in rats, equivalent to 8.1 times the recommended human clinical dose for esophageal candidiasis based on body surface area comparisons.
Aldoril D50 Patient Information
No information avaliable
Aldoril D50 Organisms Affected
Aspergillis, Candida and other fungi
