Aldoril 15 en es it fr

Aldoril 15 Brand names, Aldoril 15 Analogs

Aldoril 15 Brand Names Mixture

  • No information avaliable

Aldoril 15 Chemical_Formula


Aldoril 15 RX_link

Aldoril 15 fda sheet

Aldoril_15 FDA

Aldoril 15 msds (material safety sheet)

Aldoril_15 MSDS

Aldoril 15 Synthesis Reference

No information avaliable

Aldoril 15 Molecular Weight

1270.28 g/mol

Aldoril 15 Melting Point

No information avaliable

Aldoril 15 H2O Solubility

Freely soluble as sodium salt (> 200mg/mL)

Aldoril 15 State


Aldoril 15 LogP

No information avaliable

Aldoril 15 Dosage Forms

Powder for solution (for injection)

Aldoril 15 Indication

For use in the treatment of patients with esophageal candidiasis and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation.

Aldoril 15 Pharmacology

Formerly known as FK463, micafungin is a novel antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class. The U.S. Food and Drug Administration approved micafungin in March 2005. Micafungin inhibits an enzyme essential for fungal cell-wall synthesis and is fungicidal (lethal) for Candida. Micafungin can be used concomitantly with a variety of other drugs, including the HIV protease inhibitor ritonavir and the transplant medications cyclosporine and tacrolimus.

Aldoril 15 Absorption

No information avaliable

Aldoril 15 side effects and Toxicity

Intravenous LD50 in rats is 125mg/kg. In dogs it is >200mg/kg. No cases of overdosage have been reported. Repeated daily doses up to 8 mg/kg (maximum total dose of 896 mg) in adult patients have been administered in clinical trials with no reported dose-limiting toxicity. The minimum lethal dose is 125 mg/kg in rats, equivalent to 8.1 times the recommended human clinical dose for esophageal candidiasis based on body surface area comparisons.

Aldoril 15 Patient Information

No information avaliable

Aldoril 15 Organisms Affected

Aspergillis, Candida and other fungi