Aldoclor-150 en es it fr

Aldoclor-150 Brand names, Aldoclor-150 Analogs

Aldoclor-150 Brand Names Mixture

  • No information avaliable

Aldoclor-150 Chemical_Formula

C56H71N9O23S

Aldoclor-150 RX_link

http://www.rxlist.com/cgi/generic4/mycamine.htm

Aldoclor-150 fda sheet

Aldoclor-150 FDA

Aldoclor-150 msds (material safety sheet)

Aldoclor-150 MSDS

Aldoclor-150 Synthesis Reference

No information avaliable

Aldoclor-150 Molecular Weight

1270.28 g/mol

Aldoclor-150 Melting Point

No information avaliable

Aldoclor-150 H2O Solubility

Freely soluble as sodium salt (> 200mg/mL)

Aldoclor-150 State

Solid

Aldoclor-150 LogP

No information avaliable

Aldoclor-150 Dosage Forms

Powder for solution (for injection)

Aldoclor-150 Indication

For use in the treatment of patients with esophageal candidiasis and prophylaxis of Candida infections in patients undergoing hematopoietic stem cell transplantation.

Aldoclor-150 Pharmacology

Formerly known as FK463, micafungin is a novel antifungal agent. It is a glucan synthesis inhibitor of the echinocandin structural class. The U.S. Food and Drug Administration approved micafungin in March 2005. Micafungin inhibits an enzyme essential for fungal cell-wall synthesis and is fungicidal (lethal) for Candida. Micafungin can be used concomitantly with a variety of other drugs, including the HIV protease inhibitor ritonavir and the transplant medications cyclosporine and tacrolimus.

Aldoclor-150 Absorption

No information avaliable

Aldoclor-150 side effects and Toxicity

Intravenous LD50 in rats is 125mg/kg. In dogs it is >200mg/kg. No cases of overdosage have been reported. Repeated daily doses up to 8 mg/kg (maximum total dose of 896 mg) in adult patients have been administered in clinical trials with no reported dose-limiting toxicity. The minimum lethal dose is 125 mg/kg in rats, equivalent to 8.1 times the recommended human clinical dose for esophageal candidiasis based on body surface area comparisons.

Aldoclor-150 Patient Information

No information avaliable

Aldoclor-150 Organisms Affected

Aspergillis, Candida and other fungi