Aldesulfone Sodium
Aldesulfone Sodium Brand names, Aldesulfone Sodium Analogs
Aldesulfone Sodium Brand Names Mixture
- No information avaliable
Aldesulfone Sodium Chemical_Formula
C14H16N2O6S3
Aldesulfone Sodium RX_link
No information avaliable
Aldesulfone Sodium fda sheet
Aldesulfone Sodium msds (material safety sheet)
Aldesulfone Sodium Synthesis Reference
No information avaliable
Aldesulfone Sodium Molecular Weight
404.485 g/mol
Aldesulfone Sodium Melting Point
No information avaliable
Aldesulfone Sodium H2O Solubility
No information avaliable
Aldesulfone Sodium State
Solid
Aldesulfone Sodium LogP
-1.064
Aldesulfone Sodium Dosage Forms
Tablet
Aldesulfone Sodium Indication
For the treatment of leprosy and dermatitis herpetiformis
Aldesulfone Sodium Pharmacology
Sulfoxone is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Aldesulfone Sodium Absorption
Rapidly absorbed.
Aldesulfone Sodium side effects and Toxicity
Oral, rat LD50: 7000 mg/kg
Aldesulfone Sodium Patient Information
Aldesulfone Sodium Organisms Affected
Enteric bacteria and other eubacteria
