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Aldapsone Brand names, Aldapsone Analogs

Aldapsone Brand Names Mixture

  • No information avaliable

Aldapsone Chemical_Formula

C14H16N2O6S3

Aldapsone RX_link

No information avaliable

Aldapsone fda sheet

Aldapsone msds (material safety sheet)

Aldapsone MSDS

Aldapsone Synthesis Reference

No information avaliable

Aldapsone Molecular Weight

404.485 g/mol

Aldapsone Melting Point

No information avaliable

Aldapsone H2O Solubility

No information avaliable

Aldapsone State

Solid

Aldapsone LogP

-1.064

Aldapsone Dosage Forms

Tablet

Aldapsone Indication

For the treatment of leprosy and dermatitis herpetiformis

Aldapsone Pharmacology

Sulfoxone is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Aldapsone Absorption

Rapidly absorbed.

Aldapsone side effects and Toxicity

Oral, rat LD50: 7000 mg/kg

Aldapsone Patient Information

Aldapsone Organisms Affected

Enteric bacteria and other eubacteria