Akineton Hydrochloride
Category
Akineton Hydrochloride Brand names, Akineton Hydrochloride Analogs
Akineton Hydrochloride Brand Names Mixture
Akineton Hydrochloride Chemical_Formula
C21H29NO
Akineton Hydrochloride RX_link
http://www.rxlist.com/cgi/generic2/biperiden.htm
Akineton Hydrochloride fda sheet
Akineton Hydrochloride msds (material safety sheet)
Akineton Hydrochloride Synthesis Reference
No information avaliable
Akineton Hydrochloride Molecular Weight
311.461 g/mol
Akineton Hydrochloride Melting Point
114 oC
Akineton Hydrochloride H2O Solubility
25.1 mg/L
Akineton Hydrochloride State
Solid
Akineton Hydrochloride LogP
3.85
Akineton Hydrochloride Dosage Forms
Tablet
Akineton Hydrochloride Indication
For use as an adjunct in the therapy of all forms of parkinsonism and control of extrapyramidal disorders secondary to neuroleptic drug therapy.
Akineton Hydrochloride Pharmacology
Biperiden is a weak peripheral anticholinergic agent. It has, therefore, some antisecretory, antispasmodic and mydriatic effects. In addition, biperiden possesses nicotinolytic activity. The parenteral form of biperiden is an effective and reliable agent for the treatment of acute episodes of extrapyramidal disturbances sometimes seen during treatment with neuroleptic agents. Akathisia, akinesia, dyskinetic tremors, rigor, oculogyric crisis, spasmodic torticollis, and profuse sweating are markedly reduced or eliminated. With parenteral biperiden, these drug-induced disturbances are rapidly brought under control.
Akineton Hydrochloride Absorption
87% bioavailability
Akineton Hydrochloride side effects and Toxicity
LD50=760 mg/kg (Orally in rats). Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.
Akineton Hydrochloride Patient Information
No information avaliable
Akineton Hydrochloride Organisms Affected
Humans and other mammals
