Akineton Hydrochloride

Akineton Hydrochloride Brand names, Akineton Hydrochloride Analogs

Akineton Hydrochloride Brand Names Mixture

No information avaliable

Akineton Hydrochloride Chemical_Formula

C₂₁H₂₉NO

Akineton Hydrochloride RX_link

http://www.rxlist.com/cgi/generic2/biperiden.htm

Akineton Hydrochloride fda sheet

Akineton Hydrochloride msds (material safety sheet)

Akineton Hydrochloride Synthesis Reference

No information avaliable

Akineton Hydrochloride Molecular Weight

311.461 g/mol

Akineton Hydrochloride Melting Point

114 ^oC

Akineton Hydrochloride H₂O Solubility

25.1 mg/L

Akineton Hydrochloride State

Solid

Akineton Hydrochloride LogP

3.85

Akineton Hydrochloride Dosage Forms

Tablet

Akineton Hydrochloride Indication

For use as an adjunct in the therapy of all forms of parkinsonism and control of extrapyramidal disorders secondary to neuroleptic drug therapy.

Akineton Hydrochloride Pharmacology

Biperiden is a weak peripheral anticholinergic agent. It has, therefore, some antisecretory, antispasmodic and mydriatic effects. In addition, biperiden possesses nicotinolytic activity. The parenteral form of biperiden is an effective and reliable agent for the treatment of acute episodes of extrapyramidal disturbances sometimes seen during treatment with neuroleptic agents. Akathisia, akinesia, dyskinetic tremors, rigor, oculogyric crisis, spasmodic torticollis, and profuse sweating are markedly reduced or eliminated. With parenteral biperiden, these drug-induced disturbances are rapidly brought under control.

Akineton Hydrochloride Absorption

87% bioavailability

Akineton Hydrochloride side effects and Toxicity

LD₅₀=760 mg/kg (Orally in rats). Signs of overdose include dilated and sluggish pupils, warm, dry skin, facial flushing, decreased secretions of the mouth, pharynx, nose, and bronchi, foul-smelling breath, elevated temperature, tachycardia, cardiac arrhythmias, decreased bowel sounds, urinary retention, delirium, disorientation, anxiety, hallucinations, illusions, confusion, incoherence, agitation, hyperactivity, ataxia, loss of memory, paranoia, combativeness, and seizures.

Akineton Hydrochloride Patient Information