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Aflukin Brand names, Aflukin Analogs

Aflukin Brand Names Mixture

  • Holis 12 Pr (Aloe + Citrullus Colocynthis + Gamboge + Podophyllum + Quinine + White Hellebore Root)
  • Holis 21 (Castanea Vesca + Citrullus Colocynthis + Ipecac + Nitric Acid + Quinine + Silver Nitrate)
  • Holis 22 (Carbon Disulfide + Chenopodium Ambrosioides + Quinine Sulfate + Tobacco)
  • Holis 73 (Asafetida + Charcoal Activated + Gratiola Officinalis + Lycopodium Clavatum + Magnesium Carbonate + Potassium Carbonate + Quinine + Silver Nitrate)
  • Holis 78 (Aconitinum + Cedron + Citrullus Colocynthis + Hypericum Perforatum + Plantago Major + Quinine + Quinine Sulfate)
  • Holis 82 (Acetic Acid + Asafetida + Charcoal Activated + Magnesium Carbonate + Potassium Carbonate + Quinine + Radish + Silver Nitrate)
  • Salzmann Product M-1 Malena (Potassium Nitrate + Potassium Phosphate Dibasic + Quinine Sulfate + Sodium Chloride + Sodium Sulfate + Sodium Sulfite)
  • Thc Complex #57 (Arnica Montana + Barium Carbonate + Belladonna + Carbon Disulfide + Cinchona Officinalis + Cocculus Indicus + Conium Maculatum + Ferrum Phosphoricum + Gelsemium Sempervirens + German Chamomile + Hahnemann's Causticum + Lycopodium Clavatum + Oyster Shells + Phosphorus + Pomegranate Bark + Quinine Sulfate + Salicylic Acid + Sanguinaria Canadensis + Sulfur)
  • Triogene for (Calcium Glycerophosphate + Gentiana Lutea + Iron + Kola + Quinine)

Aflukin Chemical_Formula

C20H24N2O2

Aflukin RX_link

http://www.rxlist.com/cgi/generic3/quinine.htm

Aflukin fda sheet

Aflukin msds (material safety sheet)

Aflukin MSDS

Aflukin Synthesis Reference

Woodward, Doering, J. Am. Chem. Soc. 66, 849 (1944); 67, 860 (1945)

Aflukin Molecular Weight

324.417 g/mol

Aflukin Melting Point

57 oC

Aflukin H2O Solubility

500 mg/L

Aflukin State

Solid

Aflukin LogP

2.534

Aflukin Dosage Forms

Capsule; Drops; Injection; Tablet

Aflukin Indication

For the treatment of malaria and leg cramps

Aflukin Pharmacology

Quinine is used parenterally to treat life-threatening infections caused by chloroquine-resistant Plasmodium falciparum malaria. Quinine acts as a blood schizonticide although it also has gametocytocidal activity against P. vivax and P. malariae. Because it is a weak base, it is concentrated in the food vacuoles of P. falciparum. It is thought to act by inhibiting heme polymerase, thereby allowing accumulation of its cytotoxic substrate, heme. As a schizonticidal drug, it is less effective and more toxic than chloroquine. However, it has a special place in the management of severe falciparum malaria in areas with known resistance to chloroquine.

Aflukin Absorption

76 - 88%

Aflukin side effects and Toxicity

No information avaliable

Aflukin Patient Information

Aflukin Organisms Affected

Humans and other mammals