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Adran Brand names, Adran Analogs

Adran Brand Names Mixture

  • Dimetapp Cold and Sinus Caplets (Ibuprofen + Pseudoephedrine Hydrochloride)
  • Dristan Sinus Caplets (Ibuprofen + Pseudoephedrine Hydrochloride)

Adran Chemical_Formula

C13H18O2

Adran RX_link

http://www.rxlist.com/cgi/generic/ibup.htm

Adran fda sheet

Adran FDA

Adran msds (material safety sheet)

Adran MSDS

Adran Synthesis Reference

Nicholson, Adams; U.S. Pat. 3,228,831 (1966)

Adran Molecular Weight

206.281 g/mol

Adran Melting Point

75 - 77 oC

Adran H2O Solubility

0.049 mg/ml

Adran State

Solid

Adran LogP

3.481

Adran Dosage Forms

Tablet; Suspension

Adran Indication

For the treatment of pain (muscular and rheumatic), sprains, strains, backache and neuralgia

Adran Pharmacology

Ibuprofen is a nonsteroidal antiinflammatory drug (NSAID) with analgesic and antipyretic properties. Ibuprofen has pharmacologic actions similar to those of other prototypical NSAIAs, that is thought to be associated with the inhibition of prostaglandin synthesis. Ibuprofen is used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and to alleviate moderate pain.

Adran Absorption

rapidly absorbed

Adran side effects and Toxicity

Abdominal pain, breathing difficulties, coma, drowsiness, headache, irregular heartbeat, kidney failure, low blood pressure, nausea, ringing in the ears, seizures, sluggishness, vomiting; LD50=1255mg/kg(orally in mice)

Adran Patient Information

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation, reduce fever, and treat osteoarthritis, rheumatoid arthritis, and menstrual cramps. Inform your physician if you are pregnant or nursing. Ibuprofen should not be taken during the last three months of pregnancy. Inform your physician if you use alcohol chronically. Ibuprofen should not be taken with aspirin products. This medication should be taken with food, milk or antacids if stomach upset occurs. Ibuprofen may cause dizziness and drowsiness; use caution while driving or operating hazardous machinery. Ibuprofen may cause increased sensitivity to sunlight. Use sunscreens and wear protective clothing until degree of sensitivity is determined. Notify your physician if you develop stomach pain, bloody vomit, bloody or black tarry stools, cloudy urine, trouble breathing, rash or hives.

Adran Organisms Affected

Humans and other mammals