Adesulfone Sodium
Adesulfone Sodium Brand names, Adesulfone Sodium Analogs
Adesulfone Sodium Brand Names Mixture
- No information avaliable
Adesulfone Sodium Chemical_Formula
C14H16N2O6S3
Adesulfone Sodium RX_link
No information avaliable
Adesulfone Sodium fda sheet
Adesulfone Sodium msds (material safety sheet)
Adesulfone Sodium Synthesis Reference
No information avaliable
Adesulfone Sodium Molecular Weight
404.485 g/mol
Adesulfone Sodium Melting Point
No information avaliable
Adesulfone Sodium H2O Solubility
No information avaliable
Adesulfone Sodium State
Solid
Adesulfone Sodium LogP
-1.064
Adesulfone Sodium Dosage Forms
Tablet
Adesulfone Sodium Indication
For the treatment of leprosy and dermatitis herpetiformis
Adesulfone Sodium Pharmacology
Sulfoxone is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Adesulfone Sodium Absorption
Rapidly absorbed.
Adesulfone Sodium side effects and Toxicity
Oral, rat LD50: 7000 mg/kg
Adesulfone Sodium Patient Information
Adesulfone Sodium Organisms Affected
Enteric bacteria and other eubacteria
