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Acebutolol Brand names, Acebutolol Analogs

Acebutolol Brand Names Mixture

  • No information avaliable

Acebutolol Chemical_Formula

C18H28N2O4

Acebutolol RX_link

http://www.rxlist.com/cgi/generic2/ace.htm

Acebutolol fda sheet

Acebutolol msds (material safety sheet)

Acebutolol Synthesis Reference

No information avaliable

Acebutolol Molecular Weight

336.426 g/mol

Acebutolol Melting Point

119-123 oC

Acebutolol H2O Solubility

259 mg/L

Acebutolol State

Solid

Acebutolol LogP

2.356

Acebutolol Dosage Forms

Tablet; Capsule (200 mg and 400 mg)

Acebutolol Indication

For the management of hypertension and ventricular premature beats in adults.

Acebutolol Pharmacology

Acebutolol is a cardioselective, beta-adrenoreceptor blocking agent, which possesses mild intrinsic sympathomimetic activity (ISA) in its therapeutically effective dose range. In general, beta-blockers reduce the work the heart has to do and allow it to beat more regularly. Acebutolol has less antagonistic effects on peripheral vascular ß2-receptors at rest and after epinephrine stimulation than nonselective beta-antagonists. Low doses of acebutolol produce less evidence of bronchoconstriction than nonselective agents like propranolol but more than atenolol.

Acebutolol Absorption

Well absorbed from the Gl tract with an absolute bioavailability of approximately 40% for the parent compound. In

Acebutolol side effects and Toxicity

Symptoms of overdose include extreme bradycardia, advanced atrioventricular block, intraventricular conduction defects, hypotension, severe congestive heart failure, seizures, and in susceptible patients, bronchospasm, and hypoglycemia.

Acebutolol Patient Information

Acebutolol Organisms Affected

Humans and other mammals